RGPV B.E Computer Science 3rd Semester CBCS Syllabus

Computer Science and Engg, III-Semester

Electronic Devices & Circuits

CSE (III Sem) Electronic Device & Circuits

• Semiconductor devices, theory of P-N junction, temperature dependence and break down characteristics, junction capacitances. Zener diode, Varactor diode, PIN diode, LED, Photo diode, Transistors BJT, FET, MOSFET, types, working principal, characteristics, and region of operation, load line biasing method. Transistor as an amplifier, gain, bandwidth, frequency response, Type of amplifier.

• Feedback amplifier, negative feedback, voltage-series, voltage shunt, current series and current shunt feedback, Sinusoidal oscillators, L-C (Hartley-Colpitts) oscillators, RC phase shift, Wien bridge, and Crystal oscillators. Power amplifiers, class A, class B, class A B, C amplifiers, their efficiency and power Dissipation. 

• Switching characteristics of diode and transistor turn ON, OFF time, reverse recovery time, transistor as a switch, Multivibrators, Bistable, Monostable, Astable multivibrators. Clippers and clampers, Differential amplifier, calculation of differential, common mode gain and CMRR using h parameters.

• Operational amplifier characteristics, slew rate, full power bandwidth, offset voltage, bias current, application ,inverting , non inverting amplifier , summer, differentiator, integrator, differential amplifier, instrumentation amplifier, log and antilog amplifier , voltage to current and current to voltage converters , comparators Schmitt trigger .

• Introduction to IC, Advantages and limitations, IC classification, production process of monolithic IC, fabrication of components on monolithic IC, IC packing, general integrated circuit technology, photolithographic process, un polar IC’s, IC symbols.

References:

1. Milliman Hallkias - Integrated Electronics; TMH Pub.

2. Gayakwad; OP-amp and linear Integrated Circuits; Pearson Education

3. Salivahanan; Electronic devices and circuits; TMH

4. Robert Boylestad & Nashetsky; Electronics Devices and circuit Theory; Pearson Ed.

5. Salivahanan; Linear Integrated Circuits; TMH

6. Miliman Grabel; Micro electronics, TMH

List of Experiments:

1. Diode and Transistor characteristics

2. Transistor Applications (Amplifier and switching)

3. OP-Amp and its Applications

4. 555 timer and its Applications

Digital Circuit & Design

• Number systems & codes, Binary arithmetic, Boolean algebra and switching function. Minimization of switching function, Concept of prime implicant, Karnaugh map method, Quine McCluskey’s method,Cases with don’t care terms, Multiple output switching function.

• Introduction to logic gates, Universal gate, Half adder,Half subtractor, Full adder, Full subtractor circuits, Series & parallel addition, BCD adders, Look-ahead carry generator.

• Linear wave shaping circuits, Bistable, Monostable & Astable multivibrator, Schmitt Trigger circuits & Schmitt-Nand gates. Logic families:RTL, DTL, All types of TTL circuits, ECL, I2L, PMOS, NMOS, & CMOS logic, Gated flip- flops and gated multivibrator, Interfacing between TTL to MOS.

• Decoders, Encoders, Multiplexers, Demultiplexers, Introduction to various semiconductor memories, & designing with ROM and PLA. Introduction to Shift Registers, Counters, Synchronous & Asynchronous counters, Designing of combinational circuits like code converters.

• Introduction of Analog to Digital & Digital to Analog converters, sample & hold circuits and V-F converters.

References:

1.M. Mano; “ Digital Logic & Computer Design”; Pearson

2.Malvino Leach; “Digital Principles & Applications”;TMH

3.Millman & Taub; “Pulse Digital & Switching Waveforms”;TMH

4. W.H Gothman; “Digital Electronics”;PHI

5. R.P.Jain “Modern Digital Electronics” TMH

List of Experiments :

1.To study and test operation of all logic gates for various IC’s )IC#7400, IC#7403, IC#7408, IC#7432,

IC#7486)

2.Verification of DeMorgan’s Theorem.

3.To construct half adder and full adder.

4.To construct half subtractor and full subtractor circuits.

5.Verification of versatility of NAND gate.

6. Verification of versatility of NOR gate.

7. Designing and verification of property of full adder.

8.Design a BCD to excess-3 code convertor.

9.Design a Multiplexer/Demultiplexer

Data Structures-II

Unit- I

Introduction – Common operations on data structures, Types of data structures, Data structures &

Programming, Program Design, Complexities, Time Complexity, order of Growth, Asymptotic

Notation.

Unit- II

Advanced Data Structures-Hash tables ,Heaps , Complexity , Analysis of Heap Operations , Application

of Heap , AVL tress , Insertion & Deletion in AVL tree , Red Black Trees , Properties of Red Black

trees ,Insertion & Deletion in Red Black tree .

Unit- III

Sorting –Need for sorting , Types of sorting algorithm-Stable sorting Algorithm, Internal & External

sorting algorithm , Outline and offline algorithm ,Sorting Techniques-Insertion , Shell , Selection ,

Merge ,Quick sort, Radix sort ,bucket sort .

Unit- IV

Augmenting Data structures – Augmenting a red black trees, Retrieving an element with a given rank , Determining the rank of element ,Data structure Maintenance ,An augmentation strategy ,Interval Trees.

Unit- V

File structures- Basic file operations, File organization –Sequential file organization, Indexed sequential file organization, Direct file organization. External merge sort, Multiway Merge sort, Tournament Tree, Replacement Selection .

REFERENCES:

1. Horowitz and Sahani, “Fundamentals of data Structures”,University Press

2. Trembley and Sorenson , “Data Structures”, TMH Publications

3..A. M. Tenenbaum, “Data Structures using C & C++”, Pearson Pub

4. Venkatesan , Rose, “Data Structures” Wiley India Pvt.Ltd

5. Pai; Data structure and algorithm , TMH Publications

6. T.H.Coreman,”Introduction to algorithm”,PHI.

Discrete Structures

Unit-I

Set Theory, Relation, Function, Theorem Proving Techniques : Set Theory: Definition of sets, countable and uncountable sets, Venn Diagrams, proofs of some general identities on sets Relation: Definition, types of relation, composition of relations, Pictorial representation of relation, Equivalence relation, Partial ordering relation, Job-Scheduling problem Function: Definition, type of functions, one to one, into and onto function, inverse function, composition of functions, recursively defined functions, pigeonhole principle. Theorem proving Techniques: Mathematical induction, Proof by contradiction.

Unit-II

Algebraic Structures: Definition, Properties, types: Semi Groups, Monoid, Groups, Abelian group,

properties of groups, Subgroup, cyclic groups, Cosets, factor group, Permutation groups, Normal

subgroup, Homomorphism and isomorphism of Groups, example and standard results, Rings and Fields: definition and standard results.

Unit-III

Propositional Logic: Proposition, First order logic, Basic logical operation, truth tables, tautologies,

Contradictions, Algebra of Proposition, logical implications, logical equivalence, predicates, Normal

Forms, Universal and existential quantifiers. Introduction to finite state machine Finite state machines as models of physical system equivalence machines, Finite state machines as language recognizers

Unit-IV

Graph Theory: Introduction and basic terminology of graphs, Planer graphs, Multigraphs and weighted graphs, Isomorphic graphs, Paths, Cycles and connectivity, Shortest path in weighted graph,

Introduction to Eulerian paths and circuits, Hamiltonian paths and circuits, Graph coloring, chromatic

number, Isomorphism and Homomorphism of graphs.

Unit V

Posets, Hasse Diagram and Lattices: Introduction, ordered set, Hasse diagram of partially, ordered set, isomorphic ordered set, well ordered set, properties of Lattices, bounded and complemented lattices.

Combinatorics: Introduction, Permutation and combination, Binomial Theorem, Multimonial

Coefficients Recurrence Relation and Generating Function: Introduction to Recurrence Relation and

Recursive algorithms , Linear recurrence relations with constant coefficients, Homogeneous solutions, Particular solutions, Total solutions , Generating functions , Solution by method of generating functions.

References:

1. C.L.Liu, “Elements of Discrete Mathematics” Tata Mc Graw-Hill Edition.

2. Trembley, J.P & Manohar; “Discrete Mathematical Structure with Application CS”, McGraw Hill.

3. Kenneth H. Rosen, “Discrete Mathematics and its applications”, McGraw Hill.

4. Bisht, “Discrete Mathematics”,Oxford University Press

5. Biswal,”Discrete Mathematics & Graph Theory”, PHI

RGPV B.E 3rd Semester CBCS Syllabus.

RGPV B.E Civil 3rd Semester CBCS Syllabus

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RGPV B.E Civil 3rd Semester CBCS Syllabus

[III SEMESTER CIVIL ENGINEERING]

Material Science

UNIT I

Introduction:

Introduction to Material Science and Engineering:

Type of Materials- Metallic Materials, Polymeric Materials, Ceramic Materials, Composite Materials,

Electronic Materials, Magnetic Materials, Photonic/Optical Materials, Construction Materials, Recent

advances in Materials Science- Smart Materials, Nano Materials, Selection of Materials

Atomic Structure and Bonding:

Structure of Atoms, Atomic Numbers and Atomic Masses, Electronic structure of Atoms, Quantum

Numbers of Electrons of Atoms, Crystal and Amorphous Structure in Materials –Crystalline and

Amorphous Materials. Type of Atomic Bonds- Metallic Bonds, Covalent Bonds, Ionic Bonds,

Vander Walls Bond, Primary and Secondary Bonds.

UNIT II

Properties and Failure of Materials:-

Mechanical Properties of Materials, Thermal properties of Materials, Electrical and Magnetic

Properties of Materials, Failure of Materials –Fracture, Fatigue and Creep , Corrosion and Wear

UNIT III

Construction Materials I- Masonry and Concrete

Stones, Bricks, Their properties, Mortar-Cement and Lime mortar, Proporation, Mixing and

Properties of Mortar, Properties of Masonry, Concrete Proportioning, Properties of Fresh & Hardened

Concrete

UNIT IV

Construction Materials II- Steel , Wood & Polymers

Structural Steel, Reinforcing Steel –Grades and Types, Properties of Reinforcing Steel ,Structural

Wood, Physical Properties of Wood, Wood Products- Plywood, Particle Board, Fibre Board,

Polymers-Thermoplastics, Thermosets, Elastomers, General Properties of Polymers, Common

Polymers and their Properties, Modified Polymers, Uses of Polymers.

UNIT V

Construction Materials III- Bituminous Materials and Mixtures

Bitumen, Tar, Pitch and Asphalt, Asphalt Cement, Cut back Asphalt, Emulsified and Blown Asphalt,

Properties of Asphalts, Consistency, Rate of Curing, Resistance to Action of Water, Ductility and

Adhesion etc., Grades of Asphalt, Viscosity and Penetration Grading, Performance based Grading,

Cut back Asphalt Grades, Asphalts Concrete, Asphalt Pavement, Applications of Asphalt.

COURSE OUTCOME

The student will be able to identify the use of different materials used in civil engineering.

REFERENCES

1. DR Askeland, K Balani, The science and Engineering of Materials, Cengage Learning

2. Somayaji S., Civil Engineering Materials, 2nd ed Pearson

3. Sahu G.C, Jena J.; Building materials and Construction, Mc Graw hills, new Delhi.

4. Smith William,Hashmi J, Prakash R; Material Science & Engineering; 5ed McGraw Hill.

5. S K Duggal, Building Materials, New Age International.

6. P C Vaghese, Building Materials, PHI Learning.

7. S.C. Rangwala, Engineering Materials, Charotar.

8. R. Balasubramaniam, Material Science & Engineering, Wiley India

9. Purushattam Raj, Building materials and Techniques, Pearson

10. Mamlouk MS, Building materials and Construction Engineering 3rd, pearsons.

11. Gambhir & Jamwal, Building Materials, Mc Graw Hill.

Fluid Mechanics

UNIT I

Fundamental Fluid Properties: Engineering units of measurement, mass, density,

specific weight, specific volume, specific gravity, surface tension, capillarity, viscosity,

bulk modulus of elasticity, pressure and vapour pressure. Fluid Statics: Pressure at a

point, pressure variation in static fluid, Absolute and gauge pressure, manometers, Forces

on plane and curved surfaces (Problems on Gravity Dams and Tainter Gates), buoyant

force, stability of floating and submerged bodies, relative equilibrium.

UNIT II

Kinematics and Dynamics of Flow: Introduction to basic lines - Streamlines,

Streaklines, Pathlines. Various types of fluid flow. Velocity potential function, Stream

function, Vorticity and Circulation, Flow net. Basic equations of fluid flow like Energy

equation, continuity equation and momentum equation. Bernoulli’s equation and its

applications.

UNIT III

Laminar Flow and Turbulent Flow: Introduction to laminar & turbulent flow, Reynolds

experiment & Reynolds number. Velocity distribution, Laminar and turbulent boundary

layers and laminar sublayer, boundary layer concept, aging of pipes. Losses due to sudden

expansion and contraction, losses in pipe fittings andvalves, concepts of equivalent length,

hydraulic and energy gradient lines, siphon, pipes in series, pipes in parallel, branching of

pipes. Concept of Water Hammer transmission of power.

UNIT IV

Open channels: Channel geometry and elements of channel section, velocity distribution,

energy in open channel flow, specific energy, types of flow, critical flow and its

computations, uniform flow and its computations, Chezy’s and Manning’s formulae,

determination of normal depth and velocity, Normal and critical slopes, Economical

sections. Basic assumptions and dynamic equations of gradually varied flow,

characteristics analysis and computations of flow profiles, rapidly varied flow hydraulic

jump in rectangular channels and its basic characteristics, surges in open channels &

channel flow routing.

UNIT V

Forces on immersed bodies: Types of drag, drag on a sphere, a flat plate, a cylinder and

anaerofoil development of lift, lifting vanes, Magnus effect.

Fluid Machines: Turbines: Classifications, definitions, similarity laws, specific speed and

unit quantities, Pelton-wheel turbine-their construction and settings, speed regulation,

dimensions of various elements, Action of jet, torque, power and efficiency for ideal case,

characteristic curves. Reaction turbines: construction & setting, draft tube theory, runaway

speed, simple theory of design and characteristic curves, cavitation.

REFERENCES

 Modi & Seth , Hydraulics & Fluid Mechanics ,Rajson’s Publication Pvt Ltd

 A K Jain, Fluid Mechanics: Including Hydraulic Machines, Khanna Publisher.

 Subramanyam,Fluid Mechanics & hydraulic machines - - Tata McGraw-Hill

 R.J.Garde , Engg Fluid Mechanics , SCITECH Publishers Pvt Ltd

 Merle C. Potter, David C. Wiggert, Bassam H. Ramadan, Mechanics of Fluid, Cengage Learning.

 John F. Douglas, J.M. Gasoriek, John Swaffield, Lynne Jack, Fluid Mechanics, Pearson Education.

 K.R. Arora, Fluid Mechanics, Hydraulics and Hydraulic Machines, Standard Publishers Distributors..

 Balchandran, Engg Fluid Mechanics, PHI Learning Pvt Ltd

 Ojha & Chandramouli , Fluid Mechanics & Machinery , Oxford University Press

 Fox, Mc Donald, Pritchard Fluid Mechanicas– Wiley India, New Delhi.

 Narsimhan S Fluid Mechanics –. – University Press, Mumbai.

 Ratnam Chanamala kothapalli A.V. Fluid Mechanics & Machniery –– I.K. International, New Delhi.

 Flow Through Open Channel -- Tata McGraw-Hill

 S K Som, G Biswas, Suman Chakraborty, Introduction to Fluid Mechanics and Fluid

Machines, Tata McGraw Hill Education.

LIST OF EXPERIMENTS:-

1. To Verify Bernoull’s equation.

2. To verify Impulse Imomentum equation.

3. To find out the terminal velocity of a spherical body in water.

4. Calibration and study of Venturimeter.

5. Determination of Cc, Cv, Cd of Orifices

6. Draw characteristics Curves of Pelton Wheel Turbine.

7. Draw characteristics Curves of Francis Turbine.

8. Draw characteristics Curves of Kaplan Turbine.

9. Calibration of Nozzle meter and Mouth Piece

10. Reynolds experiment for demonstration of stream lines & turbulent flow

11. Determination of metacentric height

12. Determination of Friction Factor of a pipe

13. Determination of coefficient of discharge for a broad crested weir & to plot water

surface profile over weir.

Strength of Materials

UNIT I

Simple Stress and Strains: Concept of Elastic body stress and Strain, Hooke’s law, Various

types of stress and strains, Elastic constants, Stresses in compound bars, composite and

tapering bars, Temperature stresses. Complex Stress and Strains- Two dimensional and three

dimensional stress system. Normal and tangential stresses, Principal Planes, Principal

Stresses and Strains, Mohr’s circle of stresses.

UNIT II

Bending and Shearing Stresses: Theory of simple bending, Concept of pure bending and

bending stress, Equation of bending, Neutral axis, Section-Modulus, Differential equation of

the elastic curve, Determination of bending stresses in simply supported, Cantilever and

Overhanging beams subjected to point load and uniformly distributed loading, Bending stress

distribution across a section of beam, Shearing Stress and shear stress distribution across a

section in Beams.

UNIT III

Determination of Slope and Deflection of beams by Double Integration Method, Macaulay’s

Method, Area Moment Method, Conjugate Beam Method, and Strain Energy Method,

Castiglione’s Method, and Unit Load Method.

UNIT IV

Columns and Struts: Theory of columns, Slenderness ratio, Direct and bending stresses in short

columns, Kern of a section. Buckling and stability, Euler’s buckling/crippling load for columns with

different end conditions, Rankin’s formula, Eccentric loads and the Secant formula-Imperfections in

columns. Thin Pressure Vessels: cylinders and spheres. Stress due to internal pressure, Change

in diameter and volume. Theories of failure.

UNIT V

Torsion of Shafts: Concept of pure torsion, Torsion equation, Determination of shear stress

and angle of twist of shafts of circular section, Torsion of solid and hollow circular shafts,

Analyses of problems based on combined Bending and Torsion. Unsymmetrical Bending:

Principal moment of Inertia, Product of Inertia, Bending of a beam in a plane which is not a

plane of, symmetry. Shear center; Curved beams: Pure bending of curved beams of

rectangular, circular and trapezoidal sections, Stress distribution and position of neutral axis.

REFERENCE

1. Punmia B.C., Mechanics of Materials, , Laxmi Publications (P) Ltd.

2. S.S Bhavikaati, Strength of Materials, Vikas Publisher, new Delhi

3. Rajput R. K., Strength of Materials, S. Chand.

4. S. Ramamrutham, R. Narayanan, Strength of Materials, Dhanpat Rai Publications.

5. R. Subramaniam, Strength of Materials, Oxford University Press.

6. Sadhu Singh , Strength of Material , Khanna Publishers

7. Mubeen A , Mechanics of solids , Pearsons

8. D.S Prakash Rao, Strength of Material , University Press , Hyderabad

9. Debrath Nag, Strength of Material , Wiley

10. Jindal , Strength of Material , Pearsons.

11. Bansal R.K, Strength of Materials, Laxmi Publisher, New Delhi.

12. Nash, W.A., Strength of Materials, Mcgraw hills, New Delhi.

13. Chandramouli, Strength of Materials, PHI learning

14. Dongre A.P., Strength of Materials, Scitech, Chennai

15. Negi L. S ,Strength of Materials, McGraw Hill Professional.

16. Raj Puroshattam, Strength of Material , Pearsons

17. J.M. Gere,.J. G. Barry Mechanics of Material, Cengage Learning

LIST OF PRACTICALS

1. Study of Universal testing Machine

2. To determine the Compressive and Tensile Strength of Materials.

3. To determine the Brinell Hardness of Materials.

4. To determine the Rockwell Hardness of Materials

5. To determine the Toughness of the materials.

6. To determine the stiffness of the spring.

7. To determine the deflection of Beam by the use of deflection-beam apparatus.

DC Advance Surveying, & Remote Sensing

UNIT I

Introduction:  Basic Definitions of Surveying and Levelling , Principles , Classification of

surveying ,Methods of Linear Measurement Ranging , Accessories for linear measurement

,Chain Surveying , Compass Surveying , Plane Table Surveying , Computation of Area and

Volumes

UNIT II

Theodolite Traversing & Types: Digital levels and theodolites, Electronic

Distance measurement (EDM), Total Station and Global Positioning Systems

(GPS), Digital Planimeter.

UNIT III

Control Surveys: Providing frame work of control points, triangulation principle, co

naissance, selection and marking of stations, angle measurements and corrections, baseline

measurement and corrections, computation of sides, precise traversing.

UNIT IV

GPS Surveying:  Introduction & components of GPS, Space segment, control

segment and user segment, Elements of Satellite based surveys-Map datums, GPS

receivers, GPS observation methods and their advantages over conventional

methods.

UNIT V

Remote Sensing & GIS :  Principle, components, classification, remote sensing

data acquisition process, different types of remote sensing satellite imagery with

special relevance to Indian Remote Sensing Satellites (IRS) and applications.

GIS-Definition, components and advantages.

REFERENCES

1. B.C Punmia , Surveying Vol-II & III ,Laxmi Publication.

2. S.K. Duggal, Surveying Vol. II McGraw Hill Publishing Company Ltd.

3. Saikia MD, Das BM, Das MM, Surveying, McGraw hill

4. T.P. Kanetkar and S.V. Kulkarini Surveying and Leveling-Part-I & II , Pune

Vidyarthi Griha Prakashan, Pune.

5. Gopi A, Satikumar R- Advance surveying, Pearson

6. Remote Sensing and image interpretation by Lillesand T.M. and Kiefer R.W.

7. R.Agor, Advance Surveying ,Khanna Publisher

8. Chandra AM, Higher Surveying, New Age International, new Dwlhi

9. Bhavikatti SS, Surveying and Levelling Vol. II, I.K International

10. Venkatramaiah, Surveying, University Press, Mumbai

11. Bhatta Basudeb, , Remote Sensing and GIS, Oxford, New Delhi.

12. Subramanaian, Surveying & levelling, Oxford, New Delhi.

13.Joseph George Fundamentals of Remote Sensing

List of Practical

1. Measurement of Distance by Chaining and Ranging.

2. Locating Various Objects by Chain or Cross-Staff Surveying.

3. Measurement of bearings of sides of traverse with prismatic compass and

computation of correct included angle.

4. Determination of elevation of various points with dumpy level by collimation plane

method and rise & fall method.

5. Fixing bench mark with respect to temporary bench mark with dumpy level by fly

levelling and check levelling.

6. Measurement of vertical angles with theodolite.

7. Determination of horizontal distance between two inaccessible points with theodolite.

8. Locating given building by theodolite traversing.

DC Geology

UNIT I

Introduction and Physical Geology-  Objects and scope of geology. The crust and the interior

of the earth, origin and age of the earth, sub-aerial land, sub-terrain weathering, denudation

and deposition, wind, river, glacial and marine erosion, volcanoes, soil, formation of soil

profile ,geological classification of soil and concept of earthquake, Plate- tectonics.

Mineralogy and Crystallography- Fundamentals of mineralogy, study of common rock

forming minerals, ores and minerals of economic importance to civil engineering. elements of

crystallography and introduction to crystal systems.

Petrology: Composition of earth’s crust, study of igneous, sedimentary and

Metamorphic rocks and their formation, characteristics classification, Rocks of civil

engineering importance.

Geology of India:  Physical features of India, Brief geological history of India, occurrence of

important ores and minerals in India.

UNIT II

Structural Geology: Structures related to rocks, Dip, Strike and outcrops, Classification and

detailed studies of geological structures i.e. folds, Faults, Joints, Unconformity and their

importance in Civil Engineering.

UNIT III

Applied Geology: Introduction to applied geology and its use in civil engineering, properties

of rocks, selection of sites for roads, bridges, dams, reservoirs and tunnels. Prevention of

Engineering structures from seismic shocks, stability of hill sides, water bearing strata,

artesian wells, Use of remote-sensing techniques in selection of above sites.

UNIT IV

Remote Sensing: Basic principles, roll of remote sensing in civil engineering, components,

classification, remote sensing data acquisition process, various interpretation techniques in

remote sensing, different types of remote sensing satellite imagery with special relevance to

Indian Remote Sensing Satellites (IRS) and applications.

UNIT V

Geographic Information Systems (GIS): Definition, components and advantages, application

of geological knowledge in civil engineering projects like dams, bridges, roads, tunnels and

multistory buildings, geological factors in the design of buildings.

REFERENCE

1. Parbin Singh – “Engineering and General Geology”

2. S.K. Garg – “ A text Book of Physical and Engineering Geology”

3. Varghese P.C., Engineering Geology for civil engineering, PHI

4. A. Parthasarthy- Engineering Geology, Wiley

5. Duggal, Pandey and Rawal- Engineering Geology, Macgra Hill

6. Duggal SK, pandey, Rawal, Engineering Geology, Mc Graw Hills

7. Kamith Vasudev, Engineering Geology, University Press

8. Alam MM. Engineering Geology and Geo- Engineering, Axiom Books

9. Gangopadhay S., Engineering Geology, Oxford

10. Gulati ; Geotechnical Engineering; TMH

11. P.K. Mukerjee – “ A text Book of Geology”

12. Das and Sobhan, Principles of Geo-technical Engineering, CengageLearning

13. Kueffer and Lillesand, Remote sensing and Image interpretation

14. . Understanding GIS, ISRI Publications.

15. Valdiya K. S., Environmental Geology in Indian Context –Tata Mc Graw Hill

LIST OF EXPERIMENT

1. Identification of simple rock-forming minerals and important ores.

2. Identification of rocks.

3. Simple map Exercises.

4. Field Visit / Geological Excursion

                                             RGPV B.E 3rd Semester CBCS Syllabus.

RGPV B.E Computer Science 3rd Semester CBCS Syllabus

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RGPV B.Pharmacy 3rd Semester CBCS Syllabus

PHARMACEUTICAL CHEMISTRY-III(ORGANIC CHEMISTRY –II ) (Theory)

General methods of preparation and reaction of compounds superscripted with (*) to be explained.

To emphasize on definition, types, classification, principles/mechanisms, applications, examples

and differences:

Benzene and its derivatives

Analytical, synthetic and other evidences in the derivation of structure of benzene, Orbital picture,

resonance in benzene, aromatic characters, Huckel’s rule.

Reactions of benzene - nitration, sulphonation, halogenation- reactivity, Friedel crafts alkylationreactivity,

limitations, Friedel crafts acylation.

Substituents, effect of substituents on reactivity and orientation of mono substituted benzene

compounds towards electrophilic substitution reaction .

Structure and uses of DDT, Saccharin, BHC and Chloramine

Phenols*

Acidity of phenols, effect of substituents on acidity, qualitative tests, Structure and uses of phenol,

cresols, resorcinol, naphthols.

Aromatic Amines*

Basicity of amines, effect of substituents on basicity, and synthetic uses of aryl diazonium salts

Fats and Oils

Fatty acids – reactions.

Hydrolysis, Hydrogenation, Saponification and Rancidity of oils, Drying oils.

Analytical constants – Acid value, Saponification value, Ester value, Iodine value, Acetyl value,

Reichert Meissl (RM) value – significance and principle involved in their determination.

Polynuclear hydrocarbons

Synthesis, reactions

Structure and medicinal uses of Naphthalene, Phenanthrene, Anthracene, Diphenylmethane,

Triphenylmethane and their derivatives

Cyclo alkanes*

Stabilities – Baeyer’s strain theory, limitation of Baeyer’s strain theory, Coulson and Moffitt’s

modification, Sachse Mohr’s theory (Theory of strainless rings), reactions of cyclopropane and

cyclobutane only.

Recommended Books (Latest Editions)

1. Organic Chemistry by Morrison and Boyd

2. Organic Chemistry by I.L. Finar , Volume-I

3. Textbook of Organic Chemistry by B.S. Bahl & Arun Bahl.

4. Organic Chemistry by P.L.Soni

5. Practical Organic Chemistry by Mann and Saunders.

6. Vogel’s text book of Practical Organic Chemistry

7. Advanced Practical organic chemistry by N.K.Vishnoi.

8. Introduction to Organic Laboratory techniques by Pavia, Lampman and Kriz.

 PHARMACEUTICAL CHEMISTRY-III(ORGANIC CHEMISTRY –II ) (Practical)

1. Experiments involving laboratory techniques

 Recrystallization

 Steam distillation

2. Determination of following oil values (including standardization of reagents)

 Acid value

 Saponification value

 Iodine value

3. Preparation of compounds

 Benzanilide/Phenyl benzoate/Acetanilide from Aniline/ Phenol /Aniline by acylation

 reaction.

 2,4,6-Tribromo aniline/Para bromo acetanilide from Aniline/ Acetanilide by halogenation

 (Bromination) reaction.

 5-Nitro salicylic acid/Meta di nitro benzene from Salicylic acid / Nitro benzene by nitration

 reaction.

 Benzoic acid from Benzyl chloride by oxidation reaction.

 Benzoic acid/ Salicylic acid from alkyl benzoate/ alkyl salicylate by hydrolysis reaction.

 1-Phenyl azo-2-napthol from Aniline by diazotization and coupling reactions.

 Benzil from Benzoin by oxidation reaction.

 Dibenzal acetone from Benzaldehyde by Claison Schmidt reaction

 Cinnammic acid from Benzaldehyde by Perkin reaction

 p-Iodo benzoic acid from p-amino benzoic acid

 PHYSICAL PHARMACEUTICS-II (Theory)

Drug stability: 

Reaction kinetics: zero, pseudo-zero, first & second order, units of basic rate

constants, determination of reaction order. Physical and chemical factors influencing the

chemical degradation of pharmaceutical product: temperature, solvent, ionic strength, dielectric

constant, specific & general acid base catalysis, Simple numerical problems. Stabilization of

medicinal agents against common reactions like hydrolysis & oxidation. Accelerated stability

testing in dating of pharmaceutical dosage forms. Photolytic degradation and its prevention

Rheology: 

Newtonian systems, law of flow, kinematic viscosity, effect of temperature, nonNewtonian

systems, pseudoplastic, dilatants, plastic, thixotropy, thixotropy in formulation,

determination of viscosity, capillary, falling Sphere, rotational viscometers.

Deformation of solids: Plastic and elastic deformation, Heckel equation, Stress, Strain, Elastic

Modulus

Coarse dispersion: 

Suspension, interfacial properties of suspended particles, settling in

suspensions, formulation of suspensions, emulsions and theories of emulsification. Physical

stability of emulsions, preservation of emulsions, rheological properties of emulsions, phase

equilibria and emulsion formulation.

Surface and interfacial phenomenon: 

Liquid interface, surface & interfacial tensions, surface

free energy, measurement of surface & interfacial tensions, spreading coefficient, adsorption at

liquid interfaces, surface active agents, HLB Scale, solubilisation, detergency, adsorption at solid

interface.

Colloidal dispersions: 

Classification of dispersed systems & their general characteristics, size &

shapes of colloidal particles, classification of colloids & comparative account of their general

properties. Optical, kinetic & electrical properties. Effect of electrolytes, coacervation,

peptization & protective action.

Recommended Books: (Latest Editions)

1. Physical Pharmacy by Alfred Martin, Sixth edition

2. Experimental pharmaceutics by Eugene, Parott.

3. Tutorial pharmacy by Cooper and Gunn.

4. Stocklosam J. Pharmaceutical calculations, Lea & Febiger, Philadelphia.

5. Liberman H.A, Lachman C., Pharmaceutical Dosage forms, Tablets, Volume-1 to 3, Marcel

 Dekkar Inc.

6. Liberman H.A, Lachman C, Pharmaceutical dosage forms. Disperse systems, volume 1, 2, 3.

Marcel Dekkar Inc.

7. Physical Pharmaceutics by Ramasamy C, and Manavalan

 PHYSICAL PHARMACEUTICS- II (Practical)

 1. Determination of surface tension of given liquids by drop count and drop weight method

 2. Determination of HLB number of a surfactant by saponification method

 3. Determination of Freundlich and Langmuir constants using activated char coal

 4. Determination of critical micellar concentration of surfactants

 5. Determination of viscosity of liquid using Ostwald’s viscometer

 6. Determination sedimentation volume with effect of different suspending agent

 7. Determination sedimentation volume with effect of different concentration of single

 suspending agent

 8. Determination of viscosity of semisolid by using Brookfield viscometer

 9. Determination of reaction rate constant first order.

10. Determination of reaction rate constant second order

11. Accelerated stability studies

 HUMAN ANATOMY AND PHYSIOLOGY-II (Theory)

Body fluids and blood

Body fluids, composition and functions of blood, hemopoeisis, formation of hemoglobin, anemia,

mechanisms of coagulation, blood grouping, Rh factors, transfusion, its significance and disorders of blood.

Lymphatic system

Lymphatic organs and tissues, lymphatic vessels, lymph circulation and functions of lymphatic system

Cardiovascular system

Heart – anatomy of heart, blood circulation, blood vessels, structure and functions of artery, vein and

capillaries, elements of conduction system of heart and heart beat, its regulation by autonomic nervous  system, cardiac output, cardiac cycle. Regulation of blood pressure, pulse, electrocardiogram and disorders

of heart.

Digestive system

Anatomy of GI Tract with special reference to anatomy and functions of stomach, ( Acid production in the stomach, regulation of acid production through parasympathetic nervous system, pepsin role in protein digestion) small intestine and large intestine, anatomy and functions of salivary glands, pancreas and liver,movements of GIT, digestion and absorption of nutrients and disorders of GIT.

Respiratory system

Anatomy of respiratory system with special reference to anatomy of lungs, mechanism of respiration,

regulation of respiration, Lung volumes and capacities, transport of respiratory gases, artificial respiration,resuscitation methods.

Urinary system

Anatomy of urinary tract with special reference to anatomy of kidney and nephrons, functions of kidney and urinary tract, physiology of urine formation, micturition reflex and role of kidneys in acid base balance, role of RAS in kidney and disorders of kidney.

Reproductive system

Anatomy of male and female reproductive system, Functions of male and female reproductive system, sex hormones, physiology of menstruation, fertilization, spermatogenesis, oogenesis, pregnancy and parturition.

Introduction to genetics

Chromosomes, genes and DNA, protein synthesis, genetic pattern of inheritance

Recommended Books (Latest Editions)

1. Essentials of Medical Physiology by K. Sembulingam and P. Sembulingam. Jaypee brothers medical publishers, New Delhi.

2. Anatomy and Physiology in Health and Illness by Kathleen J.W. Wilson, Churchill Livingstone, Newyork

3. Physiological basis of Medical Practice-Best and Tailor. Williams & Wilkins Co,Riverview,MI USA

4. Text book of Medical Physiology- Arthur C,Guyton andJohn.E. Hall. Miamisburg, OH, U.S.A.

5. Principles of Anatomy and Physiology by Tortora Grabowski. Palmetto, GA, U.S.A.

6. Textbook of Human Histology by Inderbir Singh , Jaypee brothers medical publishers, New Delhi.

7. Textbook of Practical Physiology by C.L. Ghai , Jaypee brothers medical publishers, New Delhi.

8. Practical workbook of Human Physiology by K. Srinageswari and Rajeev Sharma, Jaypee brother’s medical publishers, New Delhi.

Reference Books:

1. Physiological basis of Medical Practice-Best and Tailor. Williams & Wilkins Co, Riverview, MI USA

2. Text book of Medical Physiology- Arthur C, Guyton and John. E. Hall. Miamisburg, OH, U.S.A.

3. Human Physiology (vol 1 and 2) by Dr. C.C. Chatterrje ,Academic Publishers Kolka

 HUMAN ANATOMY AND PHYSIOLOGY (Practical)

1. Introduction to hemocytometry.

2. Enumeration of white blood cell (WBC) count

3. Enumeration of total red blood corpuscles (RBC) count

4. Determination of bleeding time and clotting time

5. Determination of clotting time

6. Estimation of hemoglobin content

7. Determination of blood group.

8. Determination of erythrocyte sedimentation rate (ESR).

9. Determination of heart rate and pulse rate.

10. Recording of blood pressure.

11. Determination of tidal volume and vital capacity.

12. Study of digestive, respiratory, cardiovascular systems, urinary and reproductive systems with the help of models, charts and specimens.

13. Recording of basal mass index.

14. Study of family planning devices and pregnancy diagnosis test.

15. Demonstration of total blood count by cell analyzer.

16. Permanent slides of vital organs and gonads.

 PHARMACEUTICAL MICROBIOLOGY (Theory)

Introduction, history of microbiology, its branches, scope and its importance.

Introduction to Prokaryotes and Eukaryotes

Study of ultra-structure and morphological classification of bacteria, nutritional requirements,

raw materials used for culture media and physical parameters for growth, growth curve,

isolation and preservation methods for pure cultures, cultivation of anaerobes, quantitative

measurement of bacterial growth (total & viable count).

Study of different types of phase microscopy, dark field microscopy and electron microscopy.

Identification of bacteria using staining techniques (simple, Gram’s & Acid fast staining) and

biochemical tests (IMViC).

Study of principle, procedure, merits, demerits and applications of Physical, chemical and

mechanical method of sterilization.

Evaluation of the efficiency of sterilization methods.

Equipments employed in large scale sterilization.

Sterility indicators.

Study of morphology, classification, reproduction/replication and cultivation of Fungi and

Virus.

Classification and mode of action of disinfectants

Factors influencing disinfection, antiseptics and their evaluation.

Evaluation of bactericidal & Bacteriostatic.

Sterility testing of products (solids, liquids, ophthalmic and other sterile products) according

to IP, BP and USP.

Designing of aseptic area, laminar flow equipments; study of different sources of

contamination in an aseptic area and methods of prevention, clean area classification.

Principles and methods of different microbiological assay. Methods for standardization of

antibiotics, vitamins and amino acids.

Assessment of a new antibiotic and testing of antimicrobial activity of a new substance.

General aspects-environmental cleanliness.

Types of spoilage, factors affecting the microbial spoilage of pharmaceutical products,

sources and types of microbial contaminants, assessment of microbial contamination and

spoilage.

Preservation of pharmaceutical products using antimicrobial agents, evaluation of microbial

stability of formulations.

Growth of animal cells in culture, general procedure for cell culture, Primary, established and

transformed cell cultures.

Application of cell cultures in pharmaceutical industry and research.

Recommended Books (Latest edition)

1. W. B. Hugo and A.D. Russel: Pharmaceutical Microbiology, Blackwell Scientific

publications, Oxford London.

2. Prescott and Dunn., Industrial Microbiology, 4th edition, CBS Publishers & Distributors,

Delhi.

3. Pelczar, Chan Kreig, Microbiology, Tata McGraw Hill edn.

4. Malcolm Harris, Balliere Tindall and Cox: Pharmaceutical Microbiology.

5. Rose: Industrial Microbiology.

6. Probisher, Hinsdill et al: Fundamentals of Microbiology, 9th ed. Japan

7. Cooper and Gunn’s: Tutorial Pharmacy, CBS Publisher and Distribution.

8. Peppler: Microbial Technology.

9. I.P., B.P., U.S.P. - latest editions.

10. Ananthnarayan: Text Book of Microbiology, Orient-Longman, Chennai

11. Edward: Fundamentals of Microbiology.

12. N.K.Jain: Pharmaceutical Microbiology, Vallabh Prakashan, Delhi

13. Bergeys manual of systematic bacteriology, Williams and Wilkins- A Waverly company

 PHARMACEUTICAL MICROBIOLOGY (Practical)

1. Introduction and study of different equipments and processing, e.g., B.O.D. incubator, laminar flow, aseptic hood, autoclave, hot air sterilizer, deep freezer, refrigerator, microscopes used in experimental microbiology.

2. Sterilization of glassware, preparation and sterilization of media.

3. Sub culturing of bacteria and fungus. Nutrient stabs and slants preparations.

4. Staining methods- Simple, Grams staining and acid fast staining (Demonstration).

5. Staining methods- Simple, Grams staining and acid fast staining (Student Practical)

6. Isolation of pure culture of micro-organisms by multiple streak plate technique.

7. Microbiological assay of antibiotics by cup plate method.

8. Motility determination by Hanging drop method.

9. Sterility testing of pharmaceuticals.

10. Bacteriological analysis of water

11. Biochemical test (IMViC reactions)

12. Revision Practical Class

 BIOCHEMISTRY (Theory)

Carbohydrate metabolism

 Glycolysis – Pathway, energetics and significance

 Citric acid cycle- Pathway, energetics and significance

 HMP shunt and its significance; Glucose-6-Phosphate dehydrogenase (G6PD) deficiency

 Glycogen metabolism Pathways and glycogen storage diseases (GSD)

 Gluconeogenesis- Pathway and its significance

 Hormonal regulation of blood glucose level and Diabetes mellitus

Biological oxidation

 Electron transport chain (ETC) and its mechanism.

 Oxidative phosphorylation & its mechanism and substrate level phosphorylation

 Inhibitors ETC and oxidative phosphorylation/Uncouplers

Lipid metabolism

 β-Oxidation of saturated fatty acid (Palmitic acid)

 Formation and utilization of ketone bodies; ketoacidosis

 De novo synthesis of fatty acids (Palmitic acid)

 Biological significance of cholesterol and conversion of cholesterol into bile acids, steroid

hormone and vitamin D

 Disorders of lipid metabolism: Hypercholesterolemia, atherosclerosis, fatty liver and obesity.

Amino acid metabolism

 General reactions of amino acid metabolism: Transamination, deamination and decarboxylation,

urea cycle and its disorders

 Catabolism of phenylalanine and tyrosine and their metabolic disorders (Phenyketonuria,

Albinism, alkeptonuria, tyrosinemia)

 Synthesis and significance of biological substances; 5-HT, melatonin, dopamine, noradrenaline,

adrenaline

 Catabolism of heme; hyperbillirubinemia and jaundice

Nucleic acid metabolism and genetic information transfer

 Biosynthesis of purine and pyrimidine nucleotides

 Catabolism of purine nucleotides and hyperuricemia and gout disease

 Organization of mammalian genome

 Structure of DNA and RNA and their functions

 DNA replication (semi conservative model)

 Transcription or RNA synthesis

 Genetic code, Translation or Protein synthesis and inhibitors

Biomolecules

 Introduction, classification, chemical nature and biological role of carbohydrate, lipids, nucleic

acids, amino acids and proteins.

Bioenergetics

 Concept of free energy, undergone and exergonic reaction, Relationship between free energy,

enthalpy and entropy, Redox potential.

 Energy rich compounds; classification; biological significances of ATP and cyclic AMP

Enzymes

 Introduction, properties, nomenclature and IUB classification of enzymes

 Enzyme kinetics (Michaelis plot, Line Weaver Burke plot)

 Enzyme inhibitors with examples

 Regulation of enzymes: enzyme induction and repression, allosteric enzymes regulation

 Therapeutic and diagnostic applications of enzymes and isoenzymes

 Coenzymes –Structure and biochemical functions

Recommended Books (Latest Editions)

1. Principles of Biochemistry by Lehninger.

2. Harper’s Biochemistry by Robert K. Murry, Daryl K. Granner and Victor W. Rodwell.

3. Biochemistry by Stryer.

4. Biochemistry by D. Satyanarayan and U.Chakrapani.

5. Textbook of Biochemistry by Rama Rao.

6. Textbook of Biochemistry by Deb.

7. Outlines of Biochemistry by Conn and Stumpf

8. Practical Biochemistry by R.C. Gupta and S. Bhargavan.

9. Introduction of Practical Biochemistry by David T. Plummer. (3rd Edition)

10. Practical Biochemistry for Medical students by Rajagopal and Ramakrishna.

11. Practical Biochemistry by Harold Varley.

 BIOCHEMISTRY (Practical)

1. Qualitative analysis of carbohydrates (Glucose, Fructose, Lactose, Maltose, Sucrose and

starch)

2. Identification tests for Proteins (albumin and Casein)

3. Quantitative analysis of reducing sugars (DNSA method) and Proteins (Biuret method)

4. Qualitative analysis of urine for abnormal constituents

5. Determination of blood creatinine

6. Determination of blood sugar

7. Determination of serum total cholesterol

8. Preparation of buffer solution and measurement of pH

9. Study of enzymatic hydrolysis of starch

10. Determination of Salivary amylase activity

11. Study the effect of Temperature on Salivary amylase activity.

12. Study the effect of substrate concentration on salivary amylase activity.

 COMPUTER APPLICATIONS IN PHARMACY (Theory)

Number system: 

Binary number system, Decimal number system, Octal number system,

Hexadecimal number systems, conversion decimal to binary, binary to decimal, octal to binary etc,

binary addition, binary subtraction – One’s complement ,Two’s complement method, binary

multiplication, binary division.

Concept of Information Systems and Software:

Information gathering, requirement and feasibility

analysis, data flow diagrams, process specifications, input/output design, process life cycle, planning

and managing the project.

Web technologies: 

Introduction to HTML, XML, CSS and Programming languages, introduction to

web servers and Server Products.

Introduction to databases, MYSQL, MS ACCESS, Pharmacy Drug database.

Application of computers in Pharmacy – 

Drug information storage and retrieval, Pharmacokinetics,

Mathematical model in Drug design, Hospital and Clinical Pharmacy, Electronic Prescribing and

discharge (EP) systems, barcode medicine identification and automated dispensing of drugs, mobile

technology and adherence monitoring.

Diagnostic System, Lab-diagnostic System, Patient Monitoring System, Pharma Information System.

Bioinformatics: Introduction, Objective of Bioinformatics, Bioinformatics Databases, Concept of

Bioinformatics, Impact of Bioinformatics in Vaccine Discovery.

Computers as data analysis in Preclinical development: Chromatographic dada analysis

(CDS), Laboratory Information management System (LIMS) and Text Information Management

System (TIMS).

Recommended books (Latest edition):

1. Computer Application in Pharmacy – William E. Fassett –Lea and Febiger, 600 South

Washington Square, USA, (215) 922-1330.

2. Computer Application in Pharmaceutical Research and Development –Sean Ekins – WileyIntescience,

A John Willey and Sons, INC., Publication, USA

3. Bioinformatics (Concept, Skills and Applications) – S. C. Rastogi-CBS Publishers and

Distributiors 4596/1- A, 11 Darya Gani, New Delhi – 110 002(INDIA)

4. Microsoft office Access - 2003, Application Development Using VBA, SQL Server, DAP and

Infopath – Cary N. Prague – Wiley Dreamtech India (P) Ltd., 4435/7, Ansari Road, Daryagani,

New Delhi - 110002

 COMPUTER APPLICATIONS IN PHARMACY (Theory)

1. Design a questionnaire using a word processing package to gather information about a particular disease.

2. Create a HTML web page to show personal information.

3. Retrieve the information of a drug and its adverse effects using online tools

4. Creating mailing labels Using Label Wizard , generating label in MS WORD

5. Create a database in MS Access to store the patient information with the required fields Using access

6. Design a form in MS Access to view, add, delete and modify the patient record in the database

7. Generating report and printing the report from patient database

8. Creating invoice table using – MS Access

9. Drug information storage and retrieval using MS Access

10. Creating and working with queries in MS Access

11. Exporting Tables, Queries, Forms and Reports to web pages

12. Exporting Tables, Queries, Forms and Reports to XML pages

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