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Wednesday, August 17

RGPV B.Pharmacy 3rd Semester CBCS Syllabus

PHARMACEUTICAL CHEMISTRY-III(ORGANIC CHEMISTRY –II ) (Theory)



General methods of preparation and reaction of compounds superscripted with (*) to be explained.
To emphasize on definition, types, classification, principles/mechanisms, applications, examples
and differences:


Benzene and its derivatives
Analytical, synthetic and other evidences in the derivation of structure of benzene, Orbital picture,
resonance in benzene, aromatic characters, Huckel’s rule.

Reactions of benzene - nitration, sulphonation, halogenation- reactivity, Friedel crafts alkylationreactivity,
limitations, Friedel crafts acylation.
Substituents, effect of substituents on reactivity and orientation of mono substituted benzene
compounds towards electrophilic substitution reaction .
Structure and uses of DDT, Saccharin, BHC and Chloramine


Phenols*
Acidity of phenols, effect of substituents on acidity, qualitative tests, Structure and uses of phenol,
cresols, resorcinol, naphthols.

Aromatic Amines*
Basicity of amines, effect of substituents on basicity, and synthetic uses of aryl diazonium salts

Fats and Oils
Fatty acids – reactions.
Hydrolysis, Hydrogenation, Saponification and Rancidity of oils, Drying oils.
Analytical constants – Acid value, Saponification value, Ester value, Iodine value, Acetyl value,
Reichert Meissl (RM) value – significance and principle involved in their determination.

Polynuclear hydrocarbons
Synthesis, reactions
Structure and medicinal uses of Naphthalene, Phenanthrene, Anthracene, Diphenylmethane,
Triphenylmethane and their derivatives

Cyclo alkanes*
Stabilities – Baeyer’s strain theory, limitation of Baeyer’s strain theory, Coulson and Moffitt’s
modification, Sachse Mohr’s theory (Theory of strainless rings), reactions of cyclopropane and
cyclobutane only.

Recommended Books (Latest Editions)

1. Organic Chemistry by Morrison and Boyd
2. Organic Chemistry by I.L. Finar , Volume-I
3. Textbook of Organic Chemistry by B.S. Bahl & Arun Bahl.
4. Organic Chemistry by P.L.Soni
5. Practical Organic Chemistry by Mann and Saunders.
6. Vogel’s text book of Practical Organic Chemistry
7. Advanced Practical organic chemistry by N.K.Vishnoi.
8. Introduction to Organic Laboratory techniques by Pavia, Lampman and Kriz.




 PHARMACEUTICAL CHEMISTRY-III(ORGANIC CHEMISTRY –II ) (Practical)



1. Experiments involving laboratory techniques
 Recrystallization
 Steam distillation

2. Determination of following oil values (including standardization of reagents)
 Acid value
 Saponification value
 Iodine value

3. Preparation of compounds
 Benzanilide/Phenyl benzoate/Acetanilide from Aniline/ Phenol /Aniline by acylation
 reaction.
 2,4,6-Tribromo aniline/Para bromo acetanilide from Aniline/ Acetanilide by halogenation
 (Bromination) reaction.
 5-Nitro salicylic acid/Meta di nitro benzene from Salicylic acid / Nitro benzene by nitration
 reaction.
 Benzoic acid from Benzyl chloride by oxidation reaction.
 Benzoic acid/ Salicylic acid from alkyl benzoate/ alkyl salicylate by hydrolysis reaction.
 1-Phenyl azo-2-napthol from Aniline by diazotization and coupling reactions.
 Benzil from Benzoin by oxidation reaction.
 Dibenzal acetone from Benzaldehyde by Claison Schmidt reaction
 Cinnammic acid from Benzaldehyde by Perkin reaction
 p-Iodo benzoic acid from p-amino benzoic acid




 PHYSICAL PHARMACEUTICS-II (Theory)


Drug stability: 
Reaction kinetics: zero, pseudo-zero, first & second order, units of basic rate
constants, determination of reaction order. Physical and chemical factors influencing the
chemical degradation of pharmaceutical product: temperature, solvent, ionic strength, dielectric
constant, specific & general acid base catalysis, Simple numerical problems. Stabilization of
medicinal agents against common reactions like hydrolysis & oxidation. Accelerated stability
testing in dating of pharmaceutical dosage forms. Photolytic degradation and its prevention

Rheology: 
Newtonian systems, law of flow, kinematic viscosity, effect of temperature, nonNewtonian
systems, pseudoplastic, dilatants, plastic, thixotropy, thixotropy in formulation,
determination of viscosity, capillary, falling Sphere, rotational viscometers.
Deformation of solids: Plastic and elastic deformation, Heckel equation, Stress, Strain, Elastic
Modulus


Coarse dispersion: 
Suspension, interfacial properties of suspended particles, settling in
suspensions, formulation of suspensions, emulsions and theories of emulsification. Physical
stability of emulsions, preservation of emulsions, rheological properties of emulsions, phase
equilibria and emulsion formulation.


Surface and interfacial phenomenon: 
Liquid interface, surface & interfacial tensions, surface
free energy, measurement of surface & interfacial tensions, spreading coefficient, adsorption at
liquid interfaces, surface active agents, HLB Scale, solubilisation, detergency, adsorption at solid
interface.


Colloidal dispersions: 
Classification of dispersed systems & their general characteristics, size &
shapes of colloidal particles, classification of colloids & comparative account of their general
properties. Optical, kinetic & electrical properties. Effect of electrolytes, coacervation,
peptization & protective action.

Recommended Books: (Latest Editions)
1. Physical Pharmacy by Alfred Martin, Sixth edition
2. Experimental pharmaceutics by Eugene, Parott.
3. Tutorial pharmacy by Cooper and Gunn.
4. Stocklosam J. Pharmaceutical calculations, Lea & Febiger, Philadelphia.
5. Liberman H.A, Lachman C., Pharmaceutical Dosage forms, Tablets, Volume-1 to 3, Marcel
 Dekkar Inc.
6. Liberman H.A, Lachman C, Pharmaceutical dosage forms. Disperse systems, volume 1, 2, 3.
Marcel Dekkar Inc.
7. Physical Pharmaceutics by Ramasamy C, and Manavalan





 PHYSICAL PHARMACEUTICS- II (Practical)



 1. Determination of surface tension of given liquids by drop count and drop weight method
 2. Determination of HLB number of a surfactant by saponification method
 3. Determination of Freundlich and Langmuir constants using activated char coal
 4. Determination of critical micellar concentration of surfactants
 5. Determination of viscosity of liquid using Ostwald’s viscometer
 6. Determination sedimentation volume with effect of different suspending agent
 7. Determination sedimentation volume with effect of different concentration of single
 suspending agent
 8. Determination of viscosity of semisolid by using Brookfield viscometer
 9. Determination of reaction rate constant first order.
10. Determination of reaction rate constant second order
11. Accelerated stability studies





 HUMAN ANATOMY AND PHYSIOLOGY-II (Theory)



Body fluids and blood
Body fluids, composition and functions of blood, hemopoeisis, formation of hemoglobin, anemia,
mechanisms of coagulation, blood grouping, Rh factors, transfusion, its significance and disorders of blood.


Lymphatic system
Lymphatic organs and tissues, lymphatic vessels, lymph circulation and functions of lymphatic system

Cardiovascular system
Heart – anatomy of heart, blood circulation, blood vessels, structure and functions of artery, vein and
capillaries, elements of conduction system of heart and heart beat, its regulation by autonomic nervous  system, cardiac output, cardiac cycle. Regulation of blood pressure, pulse, electrocardiogram and disorders
of heart.

Digestive system
Anatomy of GI Tract with special reference to anatomy and functions of stomach, ( Acid production in the stomach, regulation of acid production through parasympathetic nervous system, pepsin role in protein digestion) small intestine and large intestine, anatomy and functions of salivary glands, pancreas and liver,movements of GIT, digestion and absorption of nutrients and disorders of GIT.

Respiratory system
Anatomy of respiratory system with special reference to anatomy of lungs, mechanism of respiration,
regulation of respiration, Lung volumes and capacities, transport of respiratory gases, artificial respiration,resuscitation methods.


Urinary system
Anatomy of urinary tract with special reference to anatomy of kidney and nephrons, functions of kidney and urinary tract, physiology of urine formation, micturition reflex and role of kidneys in acid base balance, role of RAS in kidney and disorders of kidney.


Reproductive system
Anatomy of male and female reproductive system, Functions of male and female reproductive system, sex hormones, physiology of menstruation, fertilization, spermatogenesis, oogenesis, pregnancy and parturition.


Introduction to genetics
Chromosomes, genes and DNA, protein synthesis, genetic pattern of inheritance


Recommended Books (Latest Editions)
1. Essentials of Medical Physiology by K. Sembulingam and P. Sembulingam. Jaypee brothers medical publishers, New Delhi.
2. Anatomy and Physiology in Health and Illness by Kathleen J.W. Wilson, Churchill Livingstone, Newyork
3. Physiological basis of Medical Practice-Best and Tailor. Williams & Wilkins Co,Riverview,MI USA
4. Text book of Medical Physiology- Arthur C,Guyton andJohn.E. Hall. Miamisburg, OH, U.S.A.
5. Principles of Anatomy and Physiology by Tortora Grabowski. Palmetto, GA, U.S.A.
6. Textbook of Human Histology by Inderbir Singh , Jaypee brothers medical publishers, New Delhi.
7. Textbook of Practical Physiology by C.L. Ghai , Jaypee brothers medical publishers, New Delhi.
8. Practical workbook of Human Physiology by K. Srinageswari and Rajeev Sharma, Jaypee brother’s medical publishers, New Delhi.

Reference Books:
1. Physiological basis of Medical Practice-Best and Tailor. Williams & Wilkins Co, Riverview, MI USA
2. Text book of Medical Physiology- Arthur C, Guyton and John. E. Hall. Miamisburg, OH, U.S.A.
3. Human Physiology (vol 1 and 2) by Dr. C.C. Chatterrje ,Academic Publishers Kolka





 HUMAN ANATOMY AND PHYSIOLOGY (Practical)




1. Introduction to hemocytometry.
2. Enumeration of white blood cell (WBC) count
3. Enumeration of total red blood corpuscles (RBC) count
4. Determination of bleeding time and clotting time
5. Determination of clotting time
6. Estimation of hemoglobin content
7. Determination of blood group.
8. Determination of erythrocyte sedimentation rate (ESR).
9. Determination of heart rate and pulse rate.
10. Recording of blood pressure.
11. Determination of tidal volume and vital capacity.
12. Study of digestive, respiratory, cardiovascular systems, urinary and reproductive systems with the help of models, charts and specimens.
13. Recording of basal mass index.
14. Study of family planning devices and pregnancy diagnosis test.
15. Demonstration of total blood count by cell analyzer.
16. Permanent slides of vital organs and gonads.




 PHARMACEUTICAL MICROBIOLOGY (Theory)




Introduction, history of microbiology, its branches, scope and its importance.
Introduction to Prokaryotes and Eukaryotes
Study of ultra-structure and morphological classification of bacteria, nutritional requirements,
raw materials used for culture media and physical parameters for growth, growth curve,
isolation and preservation methods for pure cultures, cultivation of anaerobes, quantitative
measurement of bacterial growth (total & viable count).


Study of different types of phase microscopy, dark field microscopy and electron microscopy.


Identification of bacteria using staining techniques (simple, Gram’s & Acid fast staining) and
biochemical tests (IMViC).

Study of principle, procedure, merits, demerits and applications of Physical, chemical and
mechanical method of sterilization.
Evaluation of the efficiency of sterilization methods.
Equipments employed in large scale sterilization.
Sterility indicators.


Study of morphology, classification, reproduction/replication and cultivation of Fungi and
Virus.
Classification and mode of action of disinfectants
Factors influencing disinfection, antiseptics and their evaluation.

Evaluation of bactericidal & Bacteriostatic.
Sterility testing of products (solids, liquids, ophthalmic and other sterile products) according
to IP, BP and USP.


Designing of aseptic area, laminar flow equipments; study of different sources of
contamination in an aseptic area and methods of prevention, clean area classification.
Principles and methods of different microbiological assay. Methods for standardization of
antibiotics, vitamins and amino acids.
Assessment of a new antibiotic and testing of antimicrobial activity of a new substance.
General aspects-environmental cleanliness.


Types of spoilage, factors affecting the microbial spoilage of pharmaceutical products,
sources and types of microbial contaminants, assessment of microbial contamination and
spoilage.
Preservation of pharmaceutical products using antimicrobial agents, evaluation of microbial
stability of formulations.
Growth of animal cells in culture, general procedure for cell culture, Primary, established and
transformed cell cultures.
Application of cell cultures in pharmaceutical industry and research.


Recommended Books (Latest edition)
1. W. B. Hugo and A.D. Russel: Pharmaceutical Microbiology, Blackwell Scientific
publications, Oxford London.
2. Prescott and Dunn., Industrial Microbiology, 4th edition, CBS Publishers & Distributors,
Delhi.
3. Pelczar, Chan Kreig, Microbiology, Tata McGraw Hill edn.
4. Malcolm Harris, Balliere Tindall and Cox: Pharmaceutical Microbiology.
5. Rose: Industrial Microbiology.
6. Probisher, Hinsdill et al: Fundamentals of Microbiology, 9th ed. Japan
7. Cooper and Gunn’s: Tutorial Pharmacy, CBS Publisher and Distribution.
8. Peppler: Microbial Technology.
9. I.P., B.P., U.S.P. - latest editions.
10. Ananthnarayan: Text Book of Microbiology, Orient-Longman, Chennai
11. Edward: Fundamentals of Microbiology.
12. N.K.Jain: Pharmaceutical Microbiology, Vallabh Prakashan, Delhi
13. Bergeys manual of systematic bacteriology, Williams and Wilkins- A Waverly company




 PHARMACEUTICAL MICROBIOLOGY (Practical)




1. Introduction and study of different equipments and processing, e.g., B.O.D. incubator, laminar flow, aseptic hood, autoclave, hot air sterilizer, deep freezer, refrigerator, microscopes used in experimental microbiology.
2. Sterilization of glassware, preparation and sterilization of media.
3. Sub culturing of bacteria and fungus. Nutrient stabs and slants preparations.
4. Staining methods- Simple, Grams staining and acid fast staining (Demonstration).
5. Staining methods- Simple, Grams staining and acid fast staining (Student Practical)
6. Isolation of pure culture of micro-organisms by multiple streak plate technique.
7. Microbiological assay of antibiotics by cup plate method.
8. Motility determination by Hanging drop method.
9. Sterility testing of pharmaceuticals.
10. Bacteriological analysis of water
11. Biochemical test (IMViC reactions)
12. Revision Practical Class




 BIOCHEMISTRY (Theory)




Carbohydrate metabolism

 Glycolysis – Pathway, energetics and significance
 Citric acid cycle- Pathway, energetics and significance
 HMP shunt and its significance; Glucose-6-Phosphate dehydrogenase (G6PD) deficiency
 Glycogen metabolism Pathways and glycogen storage diseases (GSD)
 Gluconeogenesis- Pathway and its significance
 Hormonal regulation of blood glucose level and Diabetes mellitus


Biological oxidation

 Electron transport chain (ETC) and its mechanism.
 Oxidative phosphorylation & its mechanism and substrate level phosphorylation
 Inhibitors ETC and oxidative phosphorylation/Uncouplers


Lipid metabolism

 β-Oxidation of saturated fatty acid (Palmitic acid)
 Formation and utilization of ketone bodies; ketoacidosis
 De novo synthesis of fatty acids (Palmitic acid)
 Biological significance of cholesterol and conversion of cholesterol into bile acids, steroid
hormone and vitamin D
 Disorders of lipid metabolism: Hypercholesterolemia, atherosclerosis, fatty liver and obesity.


Amino acid metabolism
 General reactions of amino acid metabolism: Transamination, deamination and decarboxylation,
urea cycle and its disorders
 Catabolism of phenylalanine and tyrosine and their metabolic disorders (Phenyketonuria,
Albinism, alkeptonuria, tyrosinemia)
 Synthesis and significance of biological substances; 5-HT, melatonin, dopamine, noradrenaline,
adrenaline
 Catabolism of heme; hyperbillirubinemia and jaundice


Nucleic acid metabolism and genetic information transfer

 Biosynthesis of purine and pyrimidine nucleotides
 Catabolism of purine nucleotides and hyperuricemia and gout disease
 Organization of mammalian genome
 Structure of DNA and RNA and their functions
 DNA replication (semi conservative model)
 Transcription or RNA synthesis
 Genetic code, Translation or Protein synthesis and inhibitors


Biomolecules

 Introduction, classification, chemical nature and biological role of carbohydrate, lipids, nucleic
acids, amino acids and proteins.


Bioenergetics

 Concept of free energy, undergone and exergonic reaction, Relationship between free energy,
enthalpy and entropy, Redox potential.
 Energy rich compounds; classification; biological significances of ATP and cyclic AMP


Enzymes

 Introduction, properties, nomenclature and IUB classification of enzymes
 Enzyme kinetics (Michaelis plot, Line Weaver Burke plot)
 Enzyme inhibitors with examples
 Regulation of enzymes: enzyme induction and repression, allosteric enzymes regulation
 Therapeutic and diagnostic applications of enzymes and isoenzymes
 Coenzymes –Structure and biochemical functions


Recommended Books (Latest Editions)
1. Principles of Biochemistry by Lehninger.
2. Harper’s Biochemistry by Robert K. Murry, Daryl K. Granner and Victor W. Rodwell.
3. Biochemistry by Stryer.
4. Biochemistry by D. Satyanarayan and U.Chakrapani.
5. Textbook of Biochemistry by Rama Rao.
6. Textbook of Biochemistry by Deb.
7. Outlines of Biochemistry by Conn and Stumpf
8. Practical Biochemistry by R.C. Gupta and S. Bhargavan.
9. Introduction of Practical Biochemistry by David T. Plummer. (3rd Edition)
10. Practical Biochemistry for Medical students by Rajagopal and Ramakrishna.
11. Practical Biochemistry by Harold Varley.




 BIOCHEMISTRY (Practical)




1. Qualitative analysis of carbohydrates (Glucose, Fructose, Lactose, Maltose, Sucrose and
starch)
2. Identification tests for Proteins (albumin and Casein)
3. Quantitative analysis of reducing sugars (DNSA method) and Proteins (Biuret method)
4. Qualitative analysis of urine for abnormal constituents
5. Determination of blood creatinine
6. Determination of blood sugar
7. Determination of serum total cholesterol
8. Preparation of buffer solution and measurement of pH
9. Study of enzymatic hydrolysis of starch
10. Determination of Salivary amylase activity
11. Study the effect of Temperature on Salivary amylase activity.
12. Study the effect of substrate concentration on salivary amylase activity.




 COMPUTER APPLICATIONS IN PHARMACY (Theory)




Number system: 
Binary number system, Decimal number system, Octal number system,
Hexadecimal number systems, conversion decimal to binary, binary to decimal, octal to binary etc,
binary addition, binary subtraction – One’s complement ,Two’s complement method, binary
multiplication, binary division.


Concept of Information Systems and Software:
Information gathering, requirement and feasibility
analysis, data flow diagrams, process specifications, input/output design, process life cycle, planning
and managing the project.

Web technologies: 
Introduction to HTML, XML, CSS and Programming languages, introduction to
web servers and Server Products.
Introduction to databases, MYSQL, MS ACCESS, Pharmacy Drug database.

Application of computers in Pharmacy – 
Drug information storage and retrieval, Pharmacokinetics,
Mathematical model in Drug design, Hospital and Clinical Pharmacy, Electronic Prescribing and
discharge (EP) systems, barcode medicine identification and automated dispensing of drugs, mobile
technology and adherence monitoring.

Diagnostic System, Lab-diagnostic System, Patient Monitoring System, Pharma Information System.


Bioinformatics: Introduction, Objective of Bioinformatics, Bioinformatics Databases, Concept of
Bioinformatics, Impact of Bioinformatics in Vaccine Discovery.
Computers as data analysis in Preclinical development: Chromatographic dada analysis
(CDS), Laboratory Information management System (LIMS) and Text Information Management
System (TIMS).


Recommended books (Latest edition):
1. Computer Application in Pharmacy – William E. Fassett –Lea and Febiger, 600 South
Washington Square, USA, (215) 922-1330.
2. Computer Application in Pharmaceutical Research and Development –Sean Ekins – WileyIntescience,
A John Willey and Sons, INC., Publication, USA
3. Bioinformatics (Concept, Skills and Applications) – S. C. Rastogi-CBS Publishers and
Distributiors 4596/1- A, 11 Darya Gani, New Delhi – 110 002(INDIA)
4. Microsoft office Access - 2003, Application Development Using VBA, SQL Server, DAP and
Infopath – Cary N. Prague – Wiley Dreamtech India (P) Ltd., 4435/7, Ansari Road, Daryagani,
New Delhi - 110002



 COMPUTER APPLICATIONS IN PHARMACY (Theory)



1. Design a questionnaire using a word processing package to gather information about a particular disease.
2. Create a HTML web page to show personal information.
3. Retrieve the information of a drug and its adverse effects using online tools
4. Creating mailing labels Using Label Wizard , generating label in MS WORD
5. Create a database in MS Access to store the patient information with the required fields Using access
6. Design a form in MS Access to view, add, delete and modify the patient record in the database
7. Generating report and printing the report from patient database
8. Creating invoice table using – MS Access
9. Drug information storage and retrieval using MS Access
10. Creating and working with queries in MS Access
11. Exporting Tables, Queries, Forms and Reports to web pages
12. Exporting Tables, Queries, Forms and Reports to XML pages
Sunday, January 3

RGPV B.E 2nd Sem CBCS Syllabus

 HU110 ENGLISH

COURSE OBJECTIVE: The objective of this foundational course is to develop the second language learners’ ability to use the four fundamental language skills – listening, speaking, writing and reading. The objective of this laboratory is to practice English phonetics through audio & visual aids and computer software. It intends to enable student to speak English correctly with confidence. 

COURSE CONTENT: 

Grammar – Applied Grammar and usage, Parts of Speech, Articles, Tenses, Subject-Verb Agreement, Prepositions, Active and Passive Voice, Reported Speech: Direct and Indirect, Sentence Structure, Punctuations.

Vocabulary Development – Using Dictionaries and Thesaurus, Synonyms, Antonyms, Homophones, One Word Substitution, Affixation: Prefixes & Suffixes, Derivation from root words, Jargon, Scientific Jargon. 

Developing Reading Skills – Reading Comprehension, Process, Active & Passive Reading, Reading Speed Strategies, Benefits of effective reading, note-making, note- taking, Reading comprehension of technical material and SQ3R reading technique 

Developing Writing Skills – Planning, Drafting & Editing, Writing with style, right-words selection, writing effective sentences, developing logical paragraphs, art of condensation, précis, essay, technical definition and technical description 

Business Correspondence – Business Letters, Parts & Layouts of Business Letters, Writing Resume/ Application Calling/ Sending Quotations/ Orders/ Complaints and E-mails 

Topics for the Laboratory: 

1. Basic Grammar & Vocabulary Practice (Synonyms, Antonyms, Analogies, Sentence Completion, Correctly Spelt Words, Idioms, Proverbs, Common Errors. 
2. Phonetic Symbols, Pronunciations 
3. Listening Skills – Including Listening Comprehension 
4. Extempore and JAM (Just a Minute Session) 
5. Role Play – I 
6. Role play – II 
7. Body Language 
8. Debate 
9. Oral Presentation – Preparation & Delivery using Audio – Visual Aids with stress on body language and voice modulations. (Topics to be selected by the Instructor) 

COURSE OUTCOMES Student after successful completion of course must possess sound language skills. They must also feel confident in communicating their ideas and feelings. After laboratory exercises, students must possess sound language skills. They must also feel confident in communicating their ideas to others. 

EVALUATION Evaluation will be continuous an integral part of the class as well through external assessment. Laboratory assessment will be based on assignments, presentations, and interview of each candidate. 

REFERENCES A.J. Thomson and A.V. Martinet, A Practical English Grammar, Oxford IBH Pub Sanjay Kumarm Pushp Lata, English for Effective Communication, Oxford






 COMMUNICATION HU111 

COURSE OBJECTIVE: The objective of this course is to help students to acquire reading and writing skills in a self-learning mode. 

COURSE CONTENT: 
Exercises to be performed by students: 
 Reading text selection from the list given below 
 To write a book-review 

COURSE OUTCOMES Student after successful completion of course must possess sound comprehension skills. They must also feel confident in writing reviews and comments on the read material. 

EVALUATION Evaluation will be continuous an integral part of the class. Assessment will be based on assignments, presentations, and interview of each candidate. 

REFERENCES 
1. My Experiments with Truth by Mahatma Gandhi 
2. Wings of Fire by Dr. APJ Abdul Kalam 
3. History of Everything by Stephen Hawkings 
4. A Passage to India by E.M. Forster 
5. The Argumentative Indian by Amartya Sen 
6. The Old Man and the Sea by Ernest Hemingway 
7. Life of Pi by William Dalrymple 
8. The Alchemist by Paulo Coehlo 
9. The Eighth Habbit by Stephen Covey 
10. The Road Less Travelled by M.Scott Peck




MA110 MATHEMATICS


COURSE OBJECTIVE: The objective of this foundational course is to review mathematical concepts already learnt in higher secondary. This course will also introduce fundamentals of mathematical functions, derivatives and aspects of calculus to students.

COURSE CONTENT:

Recapitulation of Mathematics: Basics of Differentiation, Rolle’s and Lagranges Theorem, Tangents and Normals, Indefinite Integral (Substitution, Integration using Trigonometric Identity & Integration by Parts & Definite Integral).

Ordinary Derivatives & Applications: Expansion of functions by Maclaurin’s & Taylor’s Theorem (One Variable), Maxima and Minima of functions of two variables, Curvature (Radius, Center & Circle of Curvature for Cartesian Coordinates), Curve Tracing.

Partial Derivatives & Applications: Definition, Euler’s Theorem for Homogeneous Functions, Differentiation of Implicit Functions, Total Differential Coefficient, Transformations of Independent Variables, Jacobians, Approximation of Errors.

Integral Calculus: Definite Integrals as a Limit of Sum, Application in Summation of series, Beta and Gamma functions (Definitions, Relation between Beta and Gamma functions, Duplication formula, Applications of Beta & Gama Functions).

Applications of Integral Calculus: Multiple Integral (Double & Triple Integrals), Change of Variables, Change the Order of Integration, Integral in Area, Volume, Surfaces & Volume of Solid of Revolution about X-Axis & Y-Axis. COURSE OUTCOMES The curriculum of the Department is designed to satisfy the diverse needs of students. Coursework is designed to provide students the opportunity to learn key concepts of mathematical functions, partial derivatives as well as fundamentals and applications of integral calculus.


EVALUATION Evaluation will be continuous an integral part of the class as well through external assessment.

REFERENCES Michael Greenberg, Advanced Engineering Mathematics, Second Edition, Pearson Education, 2002 (Indian Edition). B.V. Rammana, Higher Engineering Mathematics, Tata McGraw Hill Publishing Company, 2007. Potter, Goldberg & Edward, Advanced Engineering Mathematics, Oxford University Press. S. S. Shastry, Engineering Mathematics, PHI Learning C.B. Gupta, Engineering Mathematics I & II, McGraw Hill India, 2015.



MA111 MATHEMATICS- II 

COURSE OBJECTIVE: The objective of this foundational course is to review mathematical concepts already learnt in higher secondary. This course deep understanding of matrix, differential equations as well as a strong sense of how useful the subject can be in other disciplines of learning.

COURSE CONTENT: 

Matrices & Linear Systems: Rank of a Matrix (By reducing it to Elementary Transformation, Echelon & Normal Forms), Solution of Simultaneous equations by Elementary Transformation Methods, Consistency & Inconsistency of Equations, Eigen Values & Eigen Vectors, Cayley- Hamilton Theorem..

Ordinary Differential Equations-I: First-order differential equations (Separable, Exact, Homogeneous, Linear), Linear differential Equations with constant coefficients. Ordinary

Differential Equations-II: Homogeneous linear differential equations, Simultaneous linear differential equations. Second-Order Linear Differential Equations with Variable Coefficients: Solution by Method of Undetermined Coefficients, ByS Known Integral, Removal of First Derivative, Change of Independent Variable and Variation of Parameters.

Partial Differential Equations-I: Definition, Formulation, Solution of PDE ( By Direct Integration Method & Lagranges Method), Non-Linear Partial Differential Equation of First order {Standard I, II, III & IV), Charpit’s General Method of Solution Partial Differential equations.

Partial Differential Equations-II: Partial Differential Equations with Constant Coefficients (Second and Higher Orders Homogeneous and Non- Homogeneous equations), Partial differential Equations Reducible to equations with constant coefficients, The Method of Separation of Variables.

COURSE OUTCOMES The curriculum of the Department is designed to satisfy the diverse needs of students. Coursework is designed to provide students the opportunity to learn key concepts of matrix, differential equations and their applications.

EVALUATION Evaluation will be continuous an integral part of the class as well through external assessment.

REFERENCES Dean G. Duffy, Advanced Engineering Mathematics with MATLAB, CRC Press, 2013. E. Kreyszig, Advanced Engineering Mathematics, John Wiley & Sons Inc. Michael Greenberg, Advanced Engineering Mathematics, Second Edition, Pearson Education, 2002 (Indian Edition). B.V. Rammana, Higher Engineering Mathematics, Tata McGraw Hill Publishing Company, 2007. Shanti Narayan, A Course of Mathematical Analysis. S. Chhand & Co. Delhi. Marwaha, Introduction to Linear Algebra, PHI Learning.




ML110 ENVIRONMENTAL SCIENCES 

COURSE OBJECTIVE: This course introduces students to environment concerns. Students are expected to learn about environment, factors affecting it, environmental ethics and its protection through lectures, presentations, documentaries and field visits.

COURSE CONTENT:

Introduction: Domestic and Global Environmental concerns, principles of sustainable development, Sustainable agriculture, organic farming, bio-fuels, Threats for sustainability

Environmental Ethics & Legislations: Enforcement of Environment laws in India – The water act, The Air (Prevention and Control of Pollution) Act, 1981, The Environment (Protection) Act, 1986, Environmental Auditing

Environmental Pollution: Air Pollution – sources, types of air pollutants, National Ambient Air Quality Standards, Controlling Air Pollution. Water pollution – sources, types of water pollutants, water quality indicators, water quality standards. Soil Pollution - types of soil pollutants: industrial wastes, pesticides, fertilizers and manures, salination of soil, Controlling Soil Pollution.

Environmental Challenges: Local Challenges - Solid Waste – Impact of solid waste on natural resources, Deforestation; Global Challenges - climate change and global warming, Kyoto Protocol, Greenhouse Gases, Ways to reduce Greenhouse gases emissions, Carbon Footprint, ways to reduce carbon footprint, Carbon Trading.

Sustainable habitat, industrialisation and urbanization: Concept of Green Building, Volatile Organic Compounds (VOC), GRIHA Rating, LEED Rating, HVAC, Hybrid Car Technology, Industrial ecology, India’s renewable energy capacity. Green Technology & Green Business: Green Business, Green Computing, E-waste management.

COURSE OUTCOMES Student after successful completion of course must possess an understanding of environment, eco-system and its consequences of unbalancing the environment. After successful completion of this course, student will earn 2 credits.

EVALUATION Evaluation will be continuous an integral part of the class as well through external assessment.

REFERENCES R. Rajagopalan, Environmental Studies, Oxford IBH Pub, 2011. Kogent Learning Solutions Inc., Energy, Environment, Ecology and Society, Dreamtech, 2012. Rag, R. L, Ramesh, Lekshmi Dinachandran, Introduction to sustainable engineering.


IT110 INTRODUCTION TO INFORMATION TECHNOLOGY 


COURSE OBJECTIVE: This course introduces students about the basic fundamentals of Information Technology (IT). Students are expected to learn about applications of IT in communication, multimedia, internet and cloud computing.

COURSE CONTENT: 

Data and Information: Introduction, Type of data, Simple model of computer.

Data processing using a computer: Introduction to Operating System, Data storage Media, High capacity network storage media.

Introduction to Database Management System; Database modelling; Relational model; Distributed DBMS; Data warehouse, Data mining; Classification of Language and Applications

IT Application in Communication: Network services-telephone services, Cellular telephone services, Radio and TV broadcasting, Audio-Visual conferencing, Video-on-demand.

Internet Technology: Introduction, Working of internet, Introduction to network protocol and topologies, Types of network: LAN, WAN, Web browser.

Internet Services: E-mail, Telnet, FTP, WWW, HTML, URL.

IT Application in Multimedia: Introduction, Components of multimedia and challenges, Video compression, Video coding technology: JPEG, MPEG, And JBIG.

Introduction to cloud computing: Types, Services, Models, Characteristics, Benefits and Challenges, Application, Limitations.

IT Application in E-Commerce and E-Governance: Introduction, Different Types of E- Commerce with examples, Advantages and disadvantages, E-Commerce in India, E-Services, E-Commerce security, Internet security and ethics, Technology issues, Social issues, Introduction to E-Governance, Challenges, Application, advantages, Case study of MP-online and IRCTC

Social impact of information technology: Introduction, Social Uses of World Wide Web, Social networking Services, Privacy, security and integrity of Information ,Disaster recovery Intellectual property rights, IT Enabled Services and careers, Career in information technology, Case study of NPTEL.

References: V.Rajaraman, Introduction to Information Technology; PHI E Balagurusamy, Fundamentals of Computers, TMH Santiram Kal Basic Electronics, PHI M.N. Rao Cloud Computing, PHI.



ML110 INTRODUCTION TO CIVIL ENGINEERING

COURSE OBJECTIVE: This course introduces students to civil engineering and its sub-domains. Students are expected to learn about scope, current and future trends in infrastructure industry, jobs, innovations & research opportunities in the field of civil engineering. Course content will be covered through lectures, assignments, case-studies, presentations, documentaries and field visits.

COURSE CONTENT:

Overview of Civil Engineering, types of Infrastructures, Effect of infrastructure facilities on economy and environment, Role of Civil Engineers in the infrastructural Development Introduction to sub-domains of Civil Engineering, Size of Infrastructure Industry, emerging trends in infra spending through public and public-private partnership (PPP), talent shortage, and global trends in workforce mobility and skilldemands.

Stages in the life of construction – Design, Construction, Maintenance, Repair, Demolition/Recycling; an overview of Indian Standards, units and conversion factors for Lengths, Areas, Volumes and Weights; Opportunities and challenge of India’s Infrastructure, Interdisciplinary nature of Civil Engineering Projects.

Roads: Types of Roads, Nagpur Road Plan, Components of
Road and their function; Bridges: Important parts of bridges, classification of bridges; Types of Dams.

Properties and classification of common building materials – Stones, Bricks, Sand, Limes, Cement, Mortar, Concrete, Steel.

Overview of Indian Road Congress, National Highway Authority of India (NHAI) and American Society of Civil Engineers (ASCE), Emerging areas and new technologies in the field of civil engineering.

COURSE OUTCOMES After successful completion of course, Students are expected to possess an in-depth understanding and knowledge about the scope, current and future trends in infrastructure industry, elementary terminologies, learning resources and career-opportunities in the field of civil engineering and its allied domains.

EVALUATION Evaluation will be continuous an integral part of the class followed by final examination.

REFERENCES Elements of Civil Engineering by MD Saikia, B Mohan Das, MM Das, PHI Learning Private Limited, 2015 Prakash M.N. Shesha, Ganesh B., A Textbook on Elements of Civil Engineering, PHI Learning Pvt. Ltd. Study material provided by the instructor.




ME112 CONCEPTS IN ENGINEERING DESIGN 


COURSE OBJECTIVE: The primary objective of the course is to introduce concepts in engineering design to students from all the engineering disciplines. This course broadly covers the prerequisites for an innovative design followed by concepts of products design cycle right from planning, designing, manufacturing, distributing and its usage.

COURSE CONTENT:

Introduction to engineering Design process: Its importance, types of designs, various ways to think about design like visualization, photography etc, simplified iteration model, design versus scientific method, a problem solving methodology.

Considerations of a good design Achievement of performance requirements, Total life cycle, Regulatory and social issues in Indian context

Description of Design Process Conceptual Design, Embodiment Design, Detail Design, Planning for Manufacture, Planning for distribution, Planning for Use, Planning for the retirement of the product.

Product Design Cycle, Identification of customer needs and market research essentials, concept generation, technology and market assessment

An exposure to various aspects of design including visual, creative and user-centric design (Visual merchandising, trends, materials, technology and techniques). Evolution in Transportation and Communication Technology, Bullock Cart to Lear Jets, Personal messengers to Cell Phones, Fighter planes

Introduction to any one as a case study:

1. Communication Design
2. Industrial Design
3. IT Integrated Design
4. Textile Design
5. Inter disciplinary Design

COURSE OUTCOMES Student after successful completion of course must possess an understanding of various concepts of design, product design cycle, and significant principles inevitable for design of any engineering product or services.

EVALUATION Evaluation will be continuous an integral part of the class as well through external assessment. REFERENCES George E. Dieter and Linda C. Schmidt, Engineering Design, McGraw Hill Education (India) Pvt. Ltd. Arvid Eide, Introduction to Engineering Design, McGraw Hill. Otto. K and Wood, K, Product Design, Pearson Education.





ME110 INTRODUCTION TO MECHANICAL ENGINEERING 

COURSE OBJECTIVE: This course introduces students to mechanical engineering and its sub-domains. Students are expected to learn about scope, current and future trends, jobs, innovations & research opportunities in the field of mechanical engineering. Course content will be covered through lectures, assignments, case-studies, presentations, documentaries and field visits. COURSE

CONTENT:

What is Engineering, Who are Mechanical Engineers, Overview of Mechanical Engineering, its domains, scope and its utility in different areas; Specializations available with in mechanical Engineering (thermal, production and design) and job opportunities in mechanical Engineering.

Basic definitions of terms related to Thermodynamics, First and Second law of Thermodynamics, Properties of Steam, Introduction to Boilers, Terminology of IC Engines, Two and Four Stroke Petrol and Diesel Cycle.

Introduction to mechanical properties, basic manufacturing processes, pattern, type and its use in metal casting, Introduction of welding, brazing and soldering processes

Case study on any topic from Manufacturing Engineering Magazine Published by Society of Manufacturing Engineers (USA), Machinist Magazine, Technorama published by Institution of Engineers (India) and Manufacturing Today and any other magazine related to mechanical engineering.

Overview of American Society of Heating, Refrigerating and Air-Conditioning Engineers (ASHRAE) Society of Automotive Engineers, American Society of Mechanical Engineers (ASME); Indian Society of Mechanical Engineers (ISME) etc ; Emerging areas and new technologies in the field of mechanical engineering (3D Printing)

COURSE OUTCOMES After successful completion of course, Students are expected to possess basic understanding and knowledge about the scope, current and future trends in mechanical engineering. The versatility of the mechanical engineering branch and career-opportunities in this field will enable the students to explore the new avenues in their future endeavours.

EVALUATION Evaluation will be continuous an integral part of the class followed by final examination.

 REFERENCES Jonathan Wickert, Kemper Lewis, An Introduction to Mechanical Engineering, CENGAGE Learning. Michael Clifford, Kathy Simmons, Philip Shipway, An Introduction to Mechanical Engineering: Part 1 and Part 2, Taylor and Francis.
 
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